Key additions and revisions to the 2026 AMA CPT® Professional include restructuring of the lower extremity endovascular revascularization codes, new Category I codes for hepatic and prostate irreversible electroporation (IRE), updated codes for sacroiliac joint arthrodesis and endovascular repair of the thoracic aorta, and expansion of prostate biopsy coding. Additional coding revisions and additions affect neurointerventional embolization, carpal tunnel decompression and coronary interventions.
For lower extremity endovascular revascularization, there are several major revisions which are better delineated in the 2026 AMA CPT® Professional. The existing codes for lower extremity revascularization, 37220–37235, have been deleted. These have been replaced with 46 new codes 37254–37299, which are organized by vascular territory. The new coding structure incorporates the previously defined vascular territories of iliac, femoral/popliteal and tibial/peroneal with the addition of the inframalleolar territory. The existing hierarchy of angioplasty < stent +/- angioplasty < atherectomy +/- angioplasty < stent + atherectomy +/- angioplasty is continued in the new code set with each of these treatments now further subdivided into “straightforward” when treating a stenosis and “complex” when treating an occlusion. Note that only angioplasty can be coded for in the inframalleolar territory. There are now add-on codes for intravascular lithotripsy(ies) for the iliac and femoral/popliteal territories.
For hepatic and prostate IRE, report code 47384 for IRE of 1 or more liver tumors and code 55877 for IRE of 1 or more prostate tumors. Both codes include imaging guidance. For IRE of organs other than liver or prostate, continue to use the Category III code 0600T.
For sacroiliac joint arthrodesis, code 27278 reflects placement of an intra-articular device(s) without cortical piercing and code 27279 reflects placement of an intra-articular(s) device with piercing the lateral or medial cortices of the ilium and lateral cortex of the sacrum.
For endovascular repair of the thoracic aorta, there is a new code for deployment of a branched endograft multi piece system involving an aorta-aortic tube device with fenestration for the subclavian artery stentgraft(s) and all aortic tube endograft extensions(s) which is reported with 33882. Four codes have been revised, including 33880, 33881, 33883, and 33886. These codes include deployment of an aorta-aortic tube endograft covering the left subclavian (33880) or not covering the left subclavian (33881) or delayed placement of proximal (33883) or distal extension prothesis (33886). Note that CPT codes 33884, 33889 and 33891 have been deleted.
For prostate biopsy, there are nine new codes (55707-55715) which include both transrectal and transperoneal approach for sextant biopsy with subdivision of ultrasound-guided with and without MRI-fusion guidance as well as target lesion biopsies. Codes 55713 and 55714 detail in-bore CT or MRI guided sextant biopsy with biopsy of additional targeted lesion(s) (55713) and for targeted lesion(s) only (55714). Non-imaging-guided prostate biopsy code 55705 has been revised and code 55700 has been deleted.
For neurointerventional embolization of the central nervous system (CNS) and non-CNS head and neck, codes 61624 and 61626 have been revised and now include all radiological supervision and interpretation (RS&I), intraprocedural roadmapping, and image guidance necessary to complete the intervention.
For percutaneous decompression of the median nerve at the carpal tunnel, this can be reported with the new code 64728.
What are the new and/or revised Category III CPT codes for 2026?
There are also several new Category III codes that capture emerging technologies such as percutaneous tissue displacement, hemodynamic inferior vena cava (IVC) placement and monitoring, benign prostate ablation with high-intensity focused ultrasound (HIFU), laser ablation of breast tumors and intravascular imaging using optical coherence tomography (OCT). Due to the creation of Category I codes for hepatic and prostate IRE, existing Category III code for IRE has been revised.
For percutaneous tissue displacement, there are three add-on codes which include 1022T for intra-abdominal/pelvic structures, 1023T for intrathoracic structures and 1024T for soft tissue.
For hemodynamic IVC monitoring, codes 0981T, 0982T and 0983T have been created to describe procedures involving the use of a wireless IVC monitor with respect to both the transcatheter implantation of the device and the remote monitoring.
For ablation of benign prostate with HIFU, report code 0950T.
For laser ablation of breast tumors, report code 0970T for benign tumors and 0971T for malignant tumors.
For intravascular imaging using OCT, this can be reported with add-on codes 0984T for initial extracranial vessels and 0985T for each additional vessel as well as 0986T for an initial intracranial vessel and 0987T for each additional vessel.
Note that due to the creation of category I codes for IRE of the liver and prostate, existing Category III code 0600T has been revised to describe IRE of 1 or more tumors per organ, other than the liver or prostate.
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